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Hyperlipidemia Patient Case Studies

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Presenters

  • Overview

    Primary care is responsible for managing patients with hyperlipidemia or mixed dyslipidemia. Many of these patients present with concomitant medical problems, including diabetes, hypertension, and coronary artery disease. Statins have been consistently shown to be highly effective in treating dyslipidemias, and as a class are generally well tolerated. However, clinical concerns relating to statin therapy include myotoxicity and hepatotoxicity.

    A variety of factors contribute to this risk beyond age and gender. Most clinical issues are typically caused by innate statin metabolism associated with polypharmacy and/or a patient's genetic polymorphism, and their impact on statin efficacy, and safety.

    Join us for this online, case-based CME activity as we make diagnostic and treatment decisions for two complicated patients with dyslipidemia.

  • Disclosure of Relevant Financial Relationships

    To provide the highest quality of CME programming, and in compliance with the ACCME Standards for Commercial Support, The Omnia-Prova Education Collaborative (TOPEC) and Prova Education require that all faculty and planning committee members disclose relevant financial relationships with any commercial interest that produces healthcare goods or services. TOPEC and Prova Education assess conflict of interest with its faculty, planners, authors and reviewers of CME activities. Identified conflicts of interest are thoroughly reviewed and resolved by independent reviewers for fair balance, scientific objectivity of studies utilized in the activity and patient care recommendations. TOPEC and Prova Education are committed to providing its learners with high quality, unbiased and state-of-the-art education.

    The following faculty, reviewers and planners have reported real or apparent conflicts of interest that have been resolved:

    Faculty Author:
    Eliot A. Brinton, MD, FAHA, FNLA
    Diplomate, American Board of Clinical Lipidology
    Associate Professor, and Director, Metabolism Section
    Cardiovascular Genetics
    University of Utah School of Medicine
    Salt Lake City, UT
    Financial Relationship Disclosure
    Commercial Interest Speakers' Bureau: Abbott Laboratories, Bristol-Myers Squibb, Daiichi-Sankyo, GlaxoSmithKline, Kowa Pharmaceuticals America, Inc., Merck, Takeda Pharmaceutical Co. Ltd.
    Advisor: Amarin Corporation, Atherotech Diagnostics Lab, Daiichi-Sankyo
    Consultant: Abbott Laboratories, GlaxoSmithKline, Merck

    Reviewer:
    Brian P. McDonough, MD
    Clinical Professor of Family Medicine
    Temple University School of Medicine
    Philadelphia, PA
    Chairman, Department of Family Medicine
    St. Francis Hospital
    Wilmington, DE
    Financial Relationship Disclosure
    No relationships reported

    Planners:
    Amanda Hilferty
    Financial Relationship Disclosure
    No relationships reported

    Barry A. Fiedel, PhD
    Financial Relationship Disclosure
    No relationships reported

    Sean T. Saunders, CCMEP
    Financial Relationship Disclosure
    No relationships reported

    Lawrence Sherman, FACME, CCMEP
    Financial Relationship Disclosure
    No relationships reported

  • Target Audience

    This course is designed to meet the Continuing Medical Education needs of the practicing Family Physician, Internal Medicine Physician, Physician Assistant and Nurse Practitioner.

  • Learning Objectives

    At the conclusion of this activity, participants should be able to:

    • Understand principles of statin use in dyslipidemia management including efficacy, safety and tolerability
    • Apply key metabolic differences among the seven currently available statins with respect to: 
          - Polypharmacy (prescription, OTC, or dietary supplements)
          - Concurrent medical and/or psychological comorbidities
          - Advanced age
    • Appreciate the need to ask about erectile dysfunction in men with dyslipidemia
    • Utilize LDL-C lowering effects of statins
    • Understand emerging data regarding statin efficacy/harm
    • Appreciate current state-of-the-art regarding genetic testing in dyslipidemia management

  • Accreditation and Credit Designation Statements

    The Omnia-Prova Education Collaborative, Inc. (TOPEC) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    The Omnia-Prova Education Collaborative, Inc. designates this enduring activity for a maximum of .50 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • Commercial Support

    This activity is supported by an independent educational grant from Kowa Pharmaceuticals America, Inc. and Lilly USA, LLC.
    Original Release Date: 12/27/11
    Expiration Date: 12/27/12

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of The Omnia-Prova Education Collaborative or Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions and possible contraindications or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Please visit Prova Education to register and participate in this CME activity

  • System Requirements

    ReachMD requires a computer, tablet or mobile device and a connection to the Internet. For best results, a high-speed Internet connection is recommended (DSL/cable). We also recommend using the latest version of your favorite browser to ensure compliance with W3C standards, such as Internet Explorer, Microsoft Edge, Chrome, Firefox or Safari. Users accustomed to IE8, IE9 IE10 are advised to update their browsers for the best experience."

  • Publication Dates

    Release Date:

Recommended
Details
Presenters

  • Overview

    Primary care is responsible for managing patients with hyperlipidemia or mixed dyslipidemia. Many of these patients present with concomitant medical problems, including diabetes, hypertension, and coronary artery disease. Statins have been consistently shown to be highly effective in treating dyslipidemias, and as a class are generally well tolerated. However, clinical concerns relating to statin therapy include myotoxicity and hepatotoxicity.

    A variety of factors contribute to this risk beyond age and gender. Most clinical issues are typically caused by innate statin metabolism associated with polypharmacy and/or a patient's genetic polymorphism, and their impact on statin efficacy, and safety.

    Join us for this online, case-based CME activity as we make diagnostic and treatment decisions for two complicated patients with dyslipidemia.

  • Disclosure of Relevant Financial Relationships

    To provide the highest quality of CME programming, and in compliance with the ACCME Standards for Commercial Support, The Omnia-Prova Education Collaborative (TOPEC) and Prova Education require that all faculty and planning committee members disclose relevant financial relationships with any commercial interest that produces healthcare goods or services. TOPEC and Prova Education assess conflict of interest with its faculty, planners, authors and reviewers of CME activities. Identified conflicts of interest are thoroughly reviewed and resolved by independent reviewers for fair balance, scientific objectivity of studies utilized in the activity and patient care recommendations. TOPEC and Prova Education are committed to providing its learners with high quality, unbiased and state-of-the-art education.

    The following faculty, reviewers and planners have reported real or apparent conflicts of interest that have been resolved:

    Faculty Author:
    Eliot A. Brinton, MD, FAHA, FNLA
    Diplomate, American Board of Clinical Lipidology
    Associate Professor, and Director, Metabolism Section
    Cardiovascular Genetics
    University of Utah School of Medicine
    Salt Lake City, UT
    Financial Relationship Disclosure
    Commercial Interest Speakers' Bureau: Abbott Laboratories, Bristol-Myers Squibb, Daiichi-Sankyo, GlaxoSmithKline, Kowa Pharmaceuticals America, Inc., Merck, Takeda Pharmaceutical Co. Ltd.
    Advisor: Amarin Corporation, Atherotech Diagnostics Lab, Daiichi-Sankyo
    Consultant: Abbott Laboratories, GlaxoSmithKline, Merck

    Reviewer:
    Brian P. McDonough, MD
    Clinical Professor of Family Medicine
    Temple University School of Medicine
    Philadelphia, PA
    Chairman, Department of Family Medicine
    St. Francis Hospital
    Wilmington, DE
    Financial Relationship Disclosure
    No relationships reported

    Planners:
    Amanda Hilferty
    Financial Relationship Disclosure
    No relationships reported

    Barry A. Fiedel, PhD
    Financial Relationship Disclosure
    No relationships reported

    Sean T. Saunders, CCMEP
    Financial Relationship Disclosure
    No relationships reported

    Lawrence Sherman, FACME, CCMEP
    Financial Relationship Disclosure
    No relationships reported

  • Target Audience

    This course is designed to meet the Continuing Medical Education needs of the practicing Family Physician, Internal Medicine Physician, Physician Assistant and Nurse Practitioner.

  • Learning Objectives

    At the conclusion of this activity, participants should be able to:

    • Understand principles of statin use in dyslipidemia management including efficacy, safety and tolerability
    • Apply key metabolic differences among the seven currently available statins with respect to: 
          - Polypharmacy (prescription, OTC, or dietary supplements)
          - Concurrent medical and/or psychological comorbidities
          - Advanced age
    • Appreciate the need to ask about erectile dysfunction in men with dyslipidemia
    • Utilize LDL-C lowering effects of statins
    • Understand emerging data regarding statin efficacy/harm
    • Appreciate current state-of-the-art regarding genetic testing in dyslipidemia management

  • Accreditation and Credit Designation Statements

    The Omnia-Prova Education Collaborative, Inc. (TOPEC) is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    The Omnia-Prova Education Collaborative, Inc. designates this enduring activity for a maximum of .50 AMA PRA Category 1 CreditsTM. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

  • Commercial Support

    This activity is supported by an independent educational grant from Kowa Pharmaceuticals America, Inc. and Lilly USA, LLC.
    Original Release Date: 12/27/11
    Expiration Date: 12/27/12

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of The Omnia-Prova Education Collaborative or Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions and possible contraindications or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Please visit Prova Education to register and participate in this CME activity

  • System Requirements

    ReachMD requires a computer, tablet or mobile device and a connection to the Internet. For best results, a high-speed Internet connection is recommended (DSL/cable). We also recommend using the latest version of your favorite browser to ensure compliance with W3C standards, such as Internet Explorer, Microsoft Edge, Chrome, Firefox or Safari. Users accustomed to IE8, IE9 IE10 are advised to update their browsers for the best experience."

  • Publication Dates

    Release Date:

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